Elektrifizierung Technischer Organischer Synthesen

~Die erste große Technologieplattform mit dem Fokus auf den Transfer elektroorganischer Synthesen vom Labor in den industriellen Maßstab~


Journalpublikationen

Beteiligte Projekte

25. "From technical HCH residues to industrial relevant vicinal dichlorinated compounds: Electrochemical chlorine transfer as a strategy for waste valorisation"
S. Horsinka, D. Weis, P. Beeskow, T. Langner, J. Sauer, S. R. Waldvogel
Journal of Hazardous Materials 2026, 508, 14185.
[DOI: 10.1016/j.jhazmat.2026.141851]

EVALINA

24. "Simple and Scalable Electrochemical Reduction of Alkyl Oxalates using Carbon-based Electrodes"
S. Kissel, P. Schnieders, V. Derdau, S. R. Waldvogel
ChemSusChem 2026, 19, e202502557.
[DOI: 10.1002/cssc.202502557]

ELWIRA

23. "Electrochemical Hofmann Rearrangement to Hydrazides"
Z. Feng, D. F. Nater, T. Léautier, M. Sintes, T. Weyhermüller, S. R. Waldvogel
ChemElectroChem 2026, 13, e70151.
[DOI: 10.1002/celc.70151]

HAVANA

22. "From Polyhalo-organic and Persistent Waste to Acetals: An Electrochemical Transfer Approach"
D. Weis, S. Horsinka, R. Bhattacharya, T. Langner, S. R. Waldvogel
ACS Electrochemistry 2026, 2, 529-540.
[DOI: 10.1021/acselectrochem.5c00498]

EVALINA

ESSENZ

21. "The Electrochemical Shono Oxidation of N-Formylpyrrolidine: Mechanistic Insights from the Computational Ferrocene Electrode Model and Cyclic Voltammetry"
L. Savintseva, P. Neugebauer, D. I. Sharapa, P. Röse, U. Krewer, F. Studt
ChemElectroChem 2025, 12, e202500202.
[DOI: 10.1002/celc.202500202]

DigiE-tos

20. "Scalable Electrochemical Preparation of Spermidine and Spermine"
R. Narobe, M. N. Perner, S. Ulrich, C. Kuhwald, M. Klein, S. Rösler, B. Cezanne, S. R. Waldvogel
ACS Electrochemistry 2026, 2, 208-217.
[DOI: 10.1021/acselectrochem.5c00437]

ESSENZ

19. "Electrochemical Chlorine Shuttle from PVC Waste to Vinyl Ether Acceptors for the Synthesis of Biodegradable Polyester Precursors"
S. Becker, D. Wördehoff, D. Weis, S. Horsinka, S. R. Waldvogel, P. Besenius
Advanced Materials 2026, 38, e17489.
[DOI: 10.1002/adma.202517489]

EVALINA

18. "Electrochemical One-Step Synthesis of Alkyne Sulfonates and Sul-fonamides: Building Blocks for Highly Substituted Alkenes & 1,3-Butadienes"
M. Azizzade, F. A. Breitschaft, S. R. Waldvogel, T. Opatz
JACS Au 2025, 5, 5493-5503.
[DOI: 10.1021/jacsau.5c00972]

E-SONATA

17. "Hectogram-Scale Synthesis of Carbamates using Electrochemical Hofmann Rearrangement in Flow"
D. F. Nater, R. Zhao, J. Rocker, C. Boche, D. Yun, B. Werner, P. Löb, A. Ziogas, S. R. Waldvogel
Organic Process Research & Development 2025, 29, 2370-2377.
[DOI: 10.1021/acs.oprd.5c00234]

HAVANA

16. "Eletrochemical Dehydration Reaction"
J. Schneider, E. Lunghi, S. R. Waldvogel
ChemSusChem 2025, 18, e202501552.
[DOI: 10.1002/cssc.202501552]

E-SONATA
E-SCOPE 2

15. "Direct electrochemical deoxygenation reaction of ketones using leaded bronze cathode in formic acid"
S. Kissel, M. N. Perner, R. Narobe, K. Hochadel, M. Klein, B. Cezanne, P. Schnieders, V. Derdau, S. R. Waldvogel
Green Chemistry 2025, 27, 10801-10807.
[DOI: 10.1039/d5gc03495g]

ELWIRA 

ESSENZ

14. "Electrochemical Synthesis of Cyclic Sulfites using Diols and Sulfur Dioxide"
C. Krumbiegel, F. A. Breitschaft, S. R. Waldvogel
Chemical Communications 2025, 61, 11267-11270.
[DOI: 10.1039/D5CC02764K]

E-SONATA

13. "Selective Hydrogen Isotope Exchange on Sulfonamides, Sulfilimides and Sulfoximines by Electrochemically Generated Bases"
C. M. Stork, E. Glöckler, V. Derdau, P. Schnieders, S. R. Waldvogel
Organic & Biomolecular Chemistry 2025, 23, 6526-6532.
[DOI: 10.1039/D5OB00799B]

ELWIRA

12. "Trends and Challenges in Electrifying Technical Organic Synthesis"
P. Röse, P. Neugebauer, S. Tamang, S. R. Waldvogel, U. Krewer
Chemie Ingenieur Technik 2025, 97, 395-410.
[DOI: 10.1002/cite.202400155]

DigiE-tos; EAGLE;
E-Scope 2.0; Outreach4ETOS;
Training4ETOS

11. "Electrochemical Three-component Synthesis of Alkenesulfonates from Cinnamic Acids, SO2, and Alcohols"
P.-C. Chien, F. A. Breitschaft, H. Kelm, S. R. Waldvogel, G. Manolikakes
ChemSusChem 2025, 18, e202500186.
[DOI: 10.1002/cssc.202500186]

E-SONATA

10. "Multicomponent Electrosynthesis of Enaminyl Sulfonates Starting from Alkylamines, SO2, and Alcohols"
F. A. Breitschaft, A. L. Saak, C. Krumbiegel, A. de A. Bartolomeu, T. Weyhermüller, S. R. Waldvogel
Organic Letters 2025, 27, 1210-1215.
[DOI: 10.1021/acs.orglett.4c04746]

E-SONATA

9. "Enhancing FAIRdata by providing digital workflows from data generation to the publication of data: an open source approach described for cyclic voltammetry"
D. Herrmann, P. Hodapp, M. Starman, P.-C. Huang, C.-L. Lin, L. B. Q. Le, T. G. Fischer, C. Bizzarri, P. Röse, N. Oppel, J. Klar, P. Tremouilhac, L. Holzhauer, S. Herres-Pawlis, A. Hoffmann, T. Seitz, A. Dorn, K. Zeitler, N. Jung, S. Bräse
Chemical Science 2025, 16, 4430-4441.
[DOI: 10.1039/D4SC08620A]

ELN ELCH

8. "Design and manufacturing of integrated fluidic channels in glass parts by vat-photopolymerization additive manufacturing"
S. Liu, C. Klahn
Procedia CIRP 2024, 128, 917-922.
[DOI: 10.1016/j.procir.2024.05.099]

AMglass4EOS

7. "Practical Electrochemical Hydrogenation of Nitriles at Nickel Foam Cathode"
R. Narobe, M. N. Perner, M. de J. Gálvez-Vázquez, C. Kuhwald, M. Klein, P. Broekmann, S. Rösler, B. Cezanne, S. R. Waldvogel
Green Chemistry 2024, 26, 10567-10574.
[DOI: 10.1039/D4GC03446E]

ESSENZ

6. "Automated Optimization of the Synthesis of Alkyl Arenesulfonates in an Undivided Electrochemical Flow Cell"
M. M. Hielscher, J. Schneider, A. H. J. Lohmann, S. R. Waldvogel
ChemElectroChem 2024, 11, e202400360.
[DOI: 10.1002/celc.202400360]

E-SCOPE 2.0
E-SONATA

5. "Choice of the Right Supporting Electrolyte in Electrochemical Reductions: A Principal Component Analysis"
F. Mast, M. M. Hielscher, T. Wirtanen, M. Erichsen, J. Gauss, G. Diezemann, S. R. Waldvogel
Journal of the American Chemical Society 2024, 146, 15119-15129.
[DOI: 10.1021/jacs.4c00910]

E-SCOPE 2.0

4. "Electrochemical Hofmann Rearrangement at High Current Densities in a Simple Flow Setup"
D. F. Nater, P. Hendriks, S. R. Waldvogel
Molecular Catalysis 2024, 554, 113823.
[DOI: 10.1016/j.mcat.2024.113823]

HAVANA

3. "Electrochemical Multicomponent Synthesis to Alkyl Alkenesulfonates using Styrenes, SO2 and Alcohols"
A. de A. Bartolomeu, F. A. Breitschaft, D. Schollmeyer, R. A. Pilli, S. R. Waldvogel
Chemistry - A European Journal 2024, 30, e202400557.
[DOI: 10.1002/chem.202400557]

E-SONATA

2. "Electrochemical Synthesis of Sulfonamides in Single-Pass Flow"
J. Schneider, S. P. Blum, S. R. Waldvogel
ChemElectroChem 2023, 10, e202300456.
[DOI: 10.1002/celc.202300456]

E-SONATA

1. "LABS: Laboratory Automation and Batch Scheduling – A Modular Open Source Python Program for the Control of Automated Electrochemical Synthesis with a Web Interface"
M. M. Hielscher, M. Dörr, J. Schneider, S. R. Waldvogel
Chemistry - An Asian Journal 2023, 18, e202300380.
[DOI: 10.1002/asia.202300380]