Electrifying Technical Organic Syntheses
~the first major technology platform that drives the transfer of electroorganic syntheses from the laboratory to industrial scale~


Journal publications


Participating projects

28. "Scalable Electrochemical Clemmensen-type Deoxygenation of Aromatic Aldehydes and Ketones"
E. Plut, R. Narobe, T. B. Therambil, M. N. Perner, S. Kissel, T. Horsten, N. Aust and S. R. Waldvogel
Green Chemistry 2026, Accepted Manuscript
[DOI: 10.1039/D6GC02190E]

KADIOL

27. "Electrochemical Three-Component Synthesis of Heteroaryl Sulfonates"
P.-C. Chien, H. Kelm, G. Manolikakes
European Journal of Organic Chemistry 2026, e70600.
[DOI: 10.1002/ejoc.70600]

E-SONATA

27. "Nickel Foam Electrodes—A Versatile, Powerful, and Readily Available Tool in Electro-Organic Synthesis"
R. Narobe, J. Schneider, S. R. Waldvogel
The Chemical Record 2026, e70152.
[DOI: 10.1002/tcr.70152]

ESSENZ

E-SONATA

26. "From technical HCH residues to industrial relevant vicinal dichlorinated compounds: Electrochemical chlorine transfer as a strategy for waste valorisation"
S. Horsinka, D. Weis, P. Beeskow, T. Langner, J. Sauer, S. R. Waldvogel

Journal of Hazardous Materials 2026, 508, 14185.
[DOI: 10.1016/j.jhazmat.2026.141851]

EVALINA
E-SONATA

Balanced Scorecard

25. "Simple and Scalable Electrochemical Reduction of Alkyl Oxalates using Carbon-based Electrodes"

S. Kissel, P. Schnieders, V. Derdau, S. R. Waldvogel 

ChemSusChem 2026, 19, e202502557.
[DOI: 10.1002/cssc.202502557]

ELWIRA

24. "Electrochemical Hofmann Rearrangement to Hydrazides"
Z. Feng, D. F. Nater, T. Léautier, M. Sintes, T. Weyhermüller, S. R. Waldvogel

ChemElectroChem 2026, 13, e70151.
[DOI: 10.1002/celc.70151]

HAVANA

23. "From Polyhalo-organic and Persistent Waste to Acetals: An Electrochemical Transfer Approach"
D. Weis, S. Horsinka, R. Bhattacharya, T. Langner, S. R. Waldvogel
ACS Electrochemistry 2026, 2, 529-540. 
[DOI: 10.1021/acselectrochem.5c00498]

EVALINA
E-SONATA

22. "Electrochemical Three-Component Synthesis of Vinyl Sulfonamides via Decarboxylative Sulfonylation of Cinnamic Acids"

P.-C. Chien, H. Kelm, G. Manolikakes

ChemSusChem 202619, e202501920.

[DOI: 10.1002/cssc.202501920]

E-SONATA

21. "Scalable Electrochemical Preparation of Spermidine and Spermine"
R. Narobe, M. N. Perner, S. Ulrich, C. Kuhwald, M. Klein, S. Rösler, B. Cezanne, S. R. Waldvogel
ACS Electrochemistry 2026, 2, 208-217.
[DOI: 10.1021/acselectrochem.5c00437]

ESSENZ

20. "Electrochemical Chlorine Shuttle from PVC Waste to Vinyl Ether Acceptors for the Synthesis of Biodegradable Polyester Precursors"
S. Becker, D. Wördehoff, D. Weis, S. Horsinka, S. R. Waldvogel, P. Besenius

Advanced Materials 2026, 38, e17489.
[DOI: 10.1002/adma.202517489]

EVALINA

E-SONATA

19. "Electrochemical One-Step Synthesis of Alkyne Sulfonates and Sulfonamides: Building Blocks for Highly Substituted Alkenes & 1,3-Butadienes"
M. Azizzade, F. A. Breitschaft, S. R. Waldvogel, T. Opatz

JACS Au 2025, 5, 5493-5503.
[DOI: 10.1021/jacsau.5c00972]

E-SONATA

18. "Hectogram-Scale Synthesis of Carbamates using Electrochemical Hofmann Rearrangement in Flow"
D. F. Nater, R. Zhao, J. Rocker, C. Boche, D. Yun, B. Werner, P. Löb, A. Ziogas, S. R. Waldvogel

Organic Process Research & Development 2025, 29, 2370-2377. 
[DOI: 10.1021/acs.oprd.5c00234]

HAVANA

17. "Electrochemical Dehydration Reaction"
J. Schneider, E. Lunghi, S. R. Waldvogel

ChemSusChem 2025, 18, e202501552.
[DOI: 10.1002/cssc.202501552]

E-SONATA
E-SCOPE 2.0

16. "Direct electrochemical deoxygenation reaction of ketones using leaded bronze cathode in formic acid"
S. Kissel, M. N. Perner, R. Narobe, K. Hochadel, M. Klein, B. Cezanne, P. Schnieders, V. Derdau, S. R. Waldvogel

Green Chemistry 2025, 27, 10801-10807.
[DOI: 10.1039/d5gc03495g]

ELWIRA
ESSENZ

15. "The Electrochemical Shono Oxidation of N-Formylpyrrolidine: Mechanistic Insights from the Computational Ferrocene Electrode Model and Cyclic Voltammetry"
L. Savintseva, P. Neugebauer, D. I. Sharapa, P. Röse, U. Krewer, F. Studt
ChemElectroChem 2025, 12, e202500202.
[DOI: 10.1002/celc.202500202]

DigiE-tos

14. "Electrochemical Synthesis of Cyclic Sulfites using Diols and Sulfur Dioxide"
C. Krumbiegel, F. A. Breitschaft, S. R. Waldvogel

Chemical Communications 2025, 61, 11267-11270.
[DOI: 10.1039/D5CC02764K]

E-SONATA

13. "Selective Hydrogen Isotope Exchange on Sulfonamides, Sulfilimides and Sulfoximines by Electrochemically Generated Bases"
C. M. Stork, E. Glöckler, V. Derdau, P. Schnieders, S. R. Waldvogel

Organic & Biomolecular Chemistry 2025, 23, 6526-6532.
[DOI: 10.1039/D5OB00799B]

ELWIRA

12. "Trends and Challenges in Electrifying Technical Organic Synthesis"

P. Röse, P. Neugebauer, S. Tamang, S. R. Waldvogel, U. Krewer 

Chemie Ingenieur Technik 2025, 97, 395-410.

[DOI: 10.1002/cite.202400155]

DigiE-tos; EAGLE;
E-Scope 2.0; Outreach4ETOS;
Training4ETOS

11. "Electrochemical Three-component Synthesis of Alkenesulfonates from Cinnamic Acids, SO2, and Alcohols"
P.-C. Chien, F. A. Breitschaft, H. Kelm, S. R. Waldvogel, G. Manolikakes 

ChemSusChem 2025, 18, e202500186.

[DOI: 10.1002/cssc.202500186]

E-SONATA

10. "Multicomponent Electrosynthesis of Enaminyl Sulfonates Starting from Alkylamines, SO2, and Alcohols"
F. A. Breitschaft, A. L. Saak, C. Krumbiegel, A. de A. Bartolomeu, T. Weyhermüller, S. R. Waldvogel

Organic Letters 202527, 1210-1215.
[DOI: 10.1021/acs.orglett.4c04746]

E-SONATA

9. "Enhancing FAIRdata by providing digital workflows from data generation to the publication of data: an open source approach described for cyclic voltammetry"

D. Herrmann, P. Hodapp, M. Starman, P.-C. Huang, C.-L. Lin, L. B. Q. Le, T. G. Fischer, C. Bizzarri, P. Röse, N. Oppel, J. Klar, P. Tremouilhac, L. Holzhauer, S. Herres-Pawlis, A. Hoffmann, T. Seitz, A. Dorn, K. Zeitler, N. Jung, S. Bräse

Chemical Science 202516, 4430-4441.

[DOI: 10.1039/D4SC08620A]

ELN ELCH

8. "Design and manufacturing of integrated fluidic channels in glass parts by vat-photopolymerization additive manufacturing"
S. Liu, C. Klahn

Procedia CIRP 2024128, 917-922.
[DOI: 10.1016/j.procir.2024.05.099]

AMglass4EOS

7. "Practical Electrochemical Hydrogenation of Nitriles at Nickel Foam Cathode"
R. Narobe, M. N. Perner, M. de J. Gálvez-Vázquez, C. Kuhwald, M. Klein, P. Broekmann, S. Rösler, B. Cezanne, S. R. Waldvogel

Green Chemistry 2024, 26, 10567-10574.
[DOI: 10.1039/D4GC03446E]

ESSENZ

6. "Automated Optimization of the Synthesis of Alkyl Arenesulfonates in an Undivided Electrochemical Flow Cell"
M. M. Hielscher, J. Schneider, A. H. J. Lohmann, S. R. Waldvogel

ChemElectroChem 2024, 11, e202400360.
[DOI: 10.1002/celc.202400360]

E-SCOPE 2.0
E-SONATA

5. "Choice of the Right Supporting Electrolyte in Electrochemical Reductions: A Principal Component Analysis"
F. Mast, M. M. Hielscher, T. Wirtanen, M. Erichsen, J. Gauss, G. Diezemann, S. R. Waldvogel

Journal of the American Chemical Society 2024, 146, 15119-15129. 
[DOI: 10.1021/jacs.4c00910]

E-SCOPE 2.0

4. "Electrochemical Hofmann Rearrangement at High Current Densities in a Simple Flow Setup"
D. F. Nater, P. Hendriks, S. R. Waldvogel

Molecular Catalysis 2024554, 113823.
[DOI: 10.1016/j.mcat.2024.113823]

HAVANA

3. "Electrochemical Multicomponent Synthesis to Alkyl Alkenesulfonates using Styrenes, SO2 and Alcohols"
A. de A. Bartolomeu, F. A. Breitschaft, D. Schollmeyer, R. A. Pilli, S. R. Waldvogel

Chemistry - A European Journal 202430, e202400557.
[DOI: 10.1002/chem.202400557]

E-SONATA

2. "Electrochemical Synthesis of Sulfonamides in Single-Pass Flow"
J. Schneider, S. P. Blum, S. R. Waldvogel

ChemElectroChem 2023, 10, e202300456.
[DOI: 10.1002/celc.202300456]

E-SONATA

1. "LABS: Laboratory Automation and Batch Scheduling – A Modular Open Source Python Program for the Control of Automated Electrochemical Synthesis with a Web Interface"
M. M. Hielscher, M. Dörr, J. Schneider, S. R. Waldvogel

Chemistry - An Asian Journal 2023, 18, e202300380.
[DOI: 10.1002/asia.202300380]